Mouse Apolipoprotein A-I-binding protein(APOA1BP) ELISA kit

Code CSB-EL001914MO
Size 96T,5×96T,10×96T
Price Request a Quote or Start an on-line Chat
Trial Size 24T ELISA Kit Trial Size (Only USD$150/ kit)
* The sample kit cost can be deducted from your subsequent orders of 96T full size kits of the same analyte at 1/5 per kit, until depleted in 6 months. Apply now

Product Details

Alternative Names
Naxe ELISA Kit; Aibp ELISA Kit; Apoa1bp ELISA Kit; NAD(P)H-hydrate epimerase ELISA Kit; EC 5.1.99.6 ELISA Kit; Apolipoprotein A-I-binding protein ELISA Kit; AI-BP ELISA Kit; NAD(P)HX epimerase ELISA Kit
Abbreviation
APOA1BP
Uniprot No.
Species
Mus musculus (Mouse)
Sample Types
serum, plasma, tissue homogenates
Detection Range
9.38 pg/ml-600 pg/ml
Sensitivity
2.34 pg/mL
Assay Time
1-5h
Sample Volume
50-100ul
Detection Wavelength
450 nm
Research Area
Cardiovascular
Assay Principle
quantitative
Measurement
Sandwich
Precision
 
Linearity
 
Recovery
 
Typical Data
 
Troubleshooting
and FAQs
Storage
Store at 2-8°C. Please refer to protocol.
Lead Time
3-5 working days after you place the order, and it takes another 3-5 days for delivery via DHL or FedEx
Description

This Mouse APOA1BP ELISA Kit was designed for the quantitative measurement of Mouse APOA1BP protein in serum, plasma, tissue homogenates. It is a Sandwich ELISA kit, its detection range is 9.38 pg/ml-600 pg/ml and the sensitivity is 2.34 pg/mL.

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Target Background

Function
(From Uniprot)
Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. Accelerates cholesterol efflux from endothelial cells to high-density lipoprotein (HDL) and thereby regulates angiogenesis.
Gene References into Functions
  1. Loss of Apoa1bp increased vascular density and facilitated the recovery of blood vessel perfusion function in a hindlimb ischemia model. PMID: 28325782
  2. The Aibp gene encodes two different proteins, both targeted to the mitochondria (mAIBP) and cytosol (cAIBP) confirming the presence of dehydratase and epimerase in the cytosol and mitochondria. PMID: 24611804
  3. AI-BP plays an important role in capacitation possibly providing a link between protein phosphorylation and cholesterol efflux. PMID: 18202122
Subcellular Location
Mitochondrion. Secreted. Note=In sperm, secretion gradually increases during capacitation.
Protein Families
NnrE/AIBP family
Tissue Specificity
Detected in testis and sperm (at protein level). Expressed at high levels in heart, liver, kidney, and testis.
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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