Code | CSB-E07327m |
Size | 96T,5×96T,10×96T |
Price | Request a Quote or Start an on-line Chat |
Trial Size |
24T ELISA Kit Trial Size (Only USD$150/ kit) * The sample kit cost can be deducted from your subsequent orders of 96T full size kits of the same analyte at 1/5 per kit, until depleted in 6 months. Apply now |
This mouse FGF1 ELISA kit employs the quantitative sandwich enzyme immunoassay technique to measure the levels of mouse FGF1 in multiple samples, including serum, plasma, or tissue homogenates. It also uses the enzyme-substrate chromogenic reaction to visualize and analyze the analyte levels through the color intensity. The intensity of the colored product is in direct proportion to the FGF1 levels in the sample and is measured at 450 nm through a microplate reader.
FGF1 is involved in the modulation of various physiological processes such as cell growth, proliferation, migration, differentiation, survival, angiogenesis, wound healing, adipogenesis, and neurogenesis. FGF1 exerts these functions through binding to FGF receptors. As a neurotrophic factor, FGF1 promotes the survival and regeneration of injured nerves, and as an insulin sensitization, FGF1 effectively normalizes the hyperglycemia of type 2 diabetes without adverse effects. It has been reported that FGF1 alleviates neuronal apoptosis and consequently ameliorates Parkinson's disease (PD) by promoting PI3K/AKT signaling and inhibiting elevated ER stress. FGF1 has also been identified to participate in myogenesis and muscle regeneration. Deregulation of FGF-1 signaling is not only implicated in tumorigenesis but also is related to tumor invasion and metastasis.
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