ACTB monoclonal antibody CSB-MA011019 was produced in the mouse immunized by using the synthetic Peptide as the immunogen. The target protein ACTB is one of six different actin proteins. Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. They are involved in cell motility, structure, integrity, and intercellular signaling. This protein is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins that are ubiquitously expressed. Diseases associated with ACTB include Dystonia, Juvenile-Onset and Baraitser-Winter Syndrome 1.
This ACTB monoclonal antibody was tested in the ELISA, WB and IHC applications. It reacts with the ACTB proteins of H, R, M, Mk, Dg, Ch, Hm, Rb-origin and may be used to detect the endogenous levels of ACTB protein.