ATG10 Antibody

Datasheet

Code	CSB-PA861988LA01HU
Size	US$166
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Image	Immunofluorescent analysis of MCF-7 cells using CSB-PA861988LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) ATG10 Polyclonal antibody

Uniprot No.

Q9H0Y0

Target Names

ATG10

Alternative Names

Apg 10 antibody; APG 10L antibody; APG10 antibody; APG10 autophagy 10 like antibody; APG10 like antibody; APG10; S. cerevisiae; homolog of antibody; APG10-like antibody; APG10L antibody; ATG 10 antibody; ATG10 antibody; ATG10 autophagy related 10 homolog (S. cerevisiae) antibody; ATG10 autophagy related 10 homolog antibody; ATG10_HUMAN antibody; autophagy 10; S. cerevisiae; homolog of antibody; Autophagy related protein 10 antibody; Autophagy-related protein 10 antibody; DKFZP586I0418 antibody; FLJ13954 antibody; pp12616 antibody; Ubiquitin-like-conjugating enzyme ATG10 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Ubiquitin-like-conjugating enzyme ATG10 protein (1-50AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The ATG10 Antibody (Product code: CSB-PA861988LA01HU) is Non-conjugated. For ATG10 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA861988LB01HU	ATG10 Antibody, HRP conjugated	ELISA
FITC	CSB-PA861988LC01HU	ATG10 Antibody, FITC conjugated
Biotin	CSB-PA861988LD01HU	ATG10 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IF

Recommended Dilution

Application	Recommended Dilution
IF	1:50-1:200

Protocols

ELISA Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

E2-like enzyme involved in autophagy. Acts as an E2-like enzyme that catalyzes the conjugation of ATG12 to ATG5. ATG12 conjugation to ATG5 is required for autophagy. Likely serves as an ATG5-recognition molecule. Not involved in ATG12 conjugation to ATG3. Plays a role in adenovirus-mediated cell lysis.

Gene References into Functions

ATG10 rs1864182 gene polymorphism was associated with the decreased risk of coal workers' pneumoconiosis in a Chinese population. PMID: 28844669
Taken together with our previous findings, we have replicated our results from the rodent system in a novel human system. We have revealed a unique sequential cascade involving Atg10, Wnt5a, alpha1 integrin, and matrix metalloproteinase-3 in GS/BMP-4-induced differentiation of hiPS cells into odontoblast-like cells at a relatively early stage. PMID: 27639333
Expression of ATG10 negatively regulated by PTBP1 and is associated with metastasis of colorectal cancer cells. PMID: 27836735
Findings suggest that eQTL/meQTL variations of ATG10 could influence lung cancer survival through regulating ATG10 expression. PMID: 27225307
3 novel miRNAs, MIR4458, MIR4667-5p, and MIR4668-5p, regulate autophagy-mediated elimination of B. pseudomallei by targeting ATG10 PMID: 26151773
results suggest that genetic variants in ATG10 may implicate with breast cancer susceptibility in Chinese population. Further large and functional studies are needed to confirm our findings PMID: 23850577
Increased expression of ATG10 in colorectal cancer is associated with lymphovascular invasion and lymph node metastasis indicating that ATG10 may be a potential prognostic maker in colorectal cancer. PMID: 23285162

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Subcellular Location

Cytoplasm.

Protein Families

ATG10 family

Database Links

HGNC: 20315

OMIM: 610800

KEGG: hsa:83734

STRING: 9606.ENSP00000282185

UniGene: Hs.713698

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The Overview of Autophagy Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Autophagy

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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