ICE1 Antibody, FITC conjugated

Code CSB-PA897466LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ICE1 Polyclonal antibody
Uniprot No.
Target Names
ICE1
Alternative Names
K0947_HUMAN antibody; KIAA0947 antibody; Uncharacterized protein KIAA0947 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Little elongation complex subunit 1 protein (1213-1505AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III. Specifically acts as a scaffold protein that promotes the LEC complex formation and recruitment and RNA polymerase II occupancy at snRNA genes in subnuclear bodies.
Gene References into Functions
  1. The results indicate that p53 interferes with the interaction between ELL/EAF and ICE1 and represses transcription of small nuclear RNA genes by Pol II. PMID: 27268141
  2. Multigenerational autosomal dominant inheritance of 5p chromosomal deletions resulting in Cri-du-Chat Syndrome with SEMA5A, CTNND2, and ICE1 deficiencies has been described. PMID: 26601658
Subcellular Location
Nucleus. Nucleus, Cajal body.
Protein Families
ICE1 family
Database Links

HGNC: 29154

KEGG: hsa:23379

STRING: 9606.ENSP00000296564

UniGene: Hs.449296

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