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RAB11FIP5 Antibody

Datasheet
Code CSB-PA019159GA01HU
Size $600
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Product Details

Uniprot No.
Q9BXF6
Target Names
RAB11FIP5
Alternative Names
GAF 1 antibody; Gaf-1 antibody; GAF1 antibody; gamma SNAP associated factor 1 antibody; Gamma-SNAP-associated factor 1 antibody; KIAA0857 antibody; Phosphoprotein pp75 antibody; pp75 antibody; RAB11 family interacting protein 5 (class I) antibody; Rab11 family-interacting protein 5 antibody; Rab11 FIP5 antibody; Rab11 interacting protein antibody; Rab11 interacting protein Rip11 antibody; Rab11-FIP5 antibody; Rab11-interacting protein Rip11 antibody; Rab11fip5 antibody; RFIP5_HUMAN antibody; RIP11 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human RAB11FIP5
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Protocols
ELISA Protocol
Western Blotting(WB) Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Rab effector involved in protein trafficking from apical recycling endosomes to the apical plasma membrane. Involved in insulin granule exocytosis. May regulate V-ATPase intracellular transport in response to extracellular acidosis.
Gene References into Functions
  1. FIP5-T276 phosphorylation occurs specifically during metaphase and anaphase. PMID: 24591568
  2. FIP5-SNX18 complex plays a pivotal role in the polarized transport of apical proteins during apical lumen initiation in epithelial cells. PMID: 21969467
  3. These data introduce Rab11b as a crucial regulator and Rip11 as mediator of acidosis-induced V-ATPase traffic in duct cells of submandibular gland. PMID: 20717956
  4. analysis of the rearrangement breakpoints suggests that the reciprocal translocation may have formed secondary to incorrect repair of double strand breaks (DSBs) by nonhomologous end-joining (NHEJ). PMID: 18384058
Subcellular Location
Cytoplasm. Recycling endosome membrane; Peripheral membrane protein. Early endosome membrane; Peripheral membrane protein. Golgi apparatus membrane; Peripheral membrane protein. Cytoplasmic vesicle, secretory vesicle membrane; Peripheral membrane protein. Mitochondrion membrane; Peripheral membrane protein.
Tissue Specificity
Detected at low levels in heart, brain, placenta, lung, liver, adipocytes, kidney, spleen, skeletal muscle and pancreas.
Database Links

HGNC: 24845

OMIM: 605536

KEGG: hsa:26056

STRING: 9606.ENSP00000258098

UniGene: Hs.24557

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Related pathways
Endocytosis
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