PIK3IP1 Antibody

Code CSB-PA018002GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
PIK3IP1
Alternative Names
HGFL antibody; hHGFL(S) antibody; Kringle domain containing protein HGFL antibody; Kringle domain-containing protein HGFL antibody; MGC17330 antibody; P3IP1_HUMAN antibody; Phosphoinositide 3 kinase interacting protein 1 antibody; Phosphoinositide-3-kinase-interacting protein 1 antibody; PIK3IP1 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human PIK3IP1
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Negative regulator of hepatic phosphatidylinositol 3-kinase (PI3K) activity.
Gene References into Functions
  1. Findings indicate that colon cancer associated transcript 1 (non-protein coding) (CCAT1) was upregulated in osteosarcoma tissues and cells, and was involved in the proliferation and migration of osteosarcoma via regulating miR-148a/phosphatidyl inositol 3-kinase interacting protein 1 (PIK3IP1) signal pathway. PMID: 28549102
  2. These results suggest that the novel PI3K regulator PIK3IP1 plays an inhibitory role in T-cell activation. PMID: 22706993
  3. PIK3IP1-v1 is a novel splicing isoform of PIK3IP1. Both of them are located on cell membrane and can induce cell apoptosis. PMID: 19088825
  4. PIK3IP1 directly binds to the p110 catalytic subunit and down modulates PI3K activity. Suggested that PIK3IP1 is a new type of PI3K regulator. PMID: 17475214
  5. PIK3IP1 is an important regulator of PI3K in vivo, and its dysregulation can contribute to liver carcinogenesis PMID: 18632611

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Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Database Links

HGNC: 24942

KEGG: hsa:113791

STRING: 9606.ENSP00000215912

UniGene: Hs.26670

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