ribosomal protein S6 kinase, 70kDa, polypeptide 2;RPS6KB2;KLS;P70-beta;P70-beta-1;P70-beta-2;S6K-beta2;S6K2;SRK;STK14B;p70(S6K)-beta;p70S6Kb ;
Target details :
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates the S6 ribosomal protein and eucaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation.