SPZ1 Antibody

Code CSB-PA022644GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
SPZ1
Alternative Names
SPZ1 antibody; TSP1 antibody; Spermatogenic leucine zipper protein 1 antibody; Testis-specific protein 1 antibody; Testis-specific protein NYD-TSP1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Human SPZ1
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Transcription factor that binds to the DNA sequence 5'-CANNTG-3'(E box) and the G-box motif. May play an important role in the regulation of cell proliferation and differentiation during spermatogenesis.
Gene References into Functions
  1. SPZ1 promotes epithelial-mesenchymal transition (EMT) by trans-activating the gene of TWIST1. A clinical analysis showed a marker association of SPZ1 and TWIST1 with induction of tumorigenesis in HCC patients. PMID: 28368406
  2. highly expressed in adult testis; may play an important role in spermatogenesis in the humans PMID: 12778315
Subcellular Location
Cytoplasm. Nucleus.
Tissue Specificity
Specifically and strongly expressed in the testis. Expressed in several tumor cell lines.
Database Links

HGNC: 30721

KEGG: hsa:84654

STRING: 9606.ENSP00000369611

UniGene: Hs.519403

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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