TRIM38 Antibody

Code CSB-PA024475LA01HU
Size US$166
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  • Western blot
    All lanes: TRIM38 antibody at 4µg/ml + Jurkat whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 54 kDa
    Observed band size: 54 kDa
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TRIM38 Polyclonal antibody
Uniprot No.
Target Names
TRIM38
Alternative Names
TRIM38 antibody; RNF15 antibody; RORET antibody; E3 ubiquitin-protein ligase TRIM38 antibody; EC 2.3.2.27 antibody; RING finger protein 15 antibody; RING-type E3 ubiquitin transferase TRIM38 antibody; Tripartite motif-containing protein 38 antibody; Zinc finger protein RoRet antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human E3 ubiquitin-protein ligase TRIM38 protein (45-259AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The TRIM38 Antibody (Product code: CSB-PA024475LA01HU) is Non-conjugated. For TRIM38 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA024475LB01HU TRIM38 Antibody, HRP conjugated ELISA
FITC CSB-PA024475LC01HU TRIM38 Antibody, FITC conjugated
Biotin CSB-PA024475LD01HU TRIM38 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
E3 ubiquitin-protein ligase. Mediates 'Lys-48'-linked polyubiquitination and proteasomal degradation of the critical TLR adapter TICAM1, inhibiting TLR3-mediated type I interferon signaling.
Gene References into Functions
  1. Data suggest that mRNA/protein levels of NLRP6 are down-regulated in synovial tissues and synoviocytes of rheumatoid arthritis (RA) patients compared to osteoarthritis patients; NLRP6 provides docking site to facilitate interaction between TAB2/3 and TRIM38 in RA synoviocytes in response to TNFalpha. (NLRP6 = ; TAB2/3 = transforming growth factor-b-activated kinase 1-binding protein 2/3; TRIM38 = tripartite motif 38) PMID: 28295271
  2. TRIM38 may act as a novel negative regulator for TLR3-mediated type I interferon signaling by targeting TRIF for degradation PMID: 23056470
  3. NF-kappaB is activated in response to TRIM38. PMID: 21789858
  4. Enterovirus 71 infection induces degradation of TRIM38. PMID: 21306652
Tissue Specificity
Ubiquitous.
Database Links

HGNC: 10059

KEGG: hsa:10475

STRING: 9606.ENSP00000230099

UniGene: Hs.584851

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