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Home > Recombinant Protein > Recombinant human Interleukin-15 protein
Product Name:

Recombinant human Interleukin-15 protein

Product Type:
 Recombinant Protein
Application:
 Immunogen，ELISA
Code:
 CSB-RP066374h
Relevance:
 Cytokine that stimulates the proliferation of T-lymphocytes. Stimulation by IL-15 requires interaction of IL-15 with components of IL-2R, including IL-2R beta and probably IL-2R gamma but not IL-2R alpha.
Mol. Weight:
 19 KD
Product Info:
 HIS-tagged
Purity:
 90%
Image:
Storage Buffer:
 PBS buffer
Storage:
 Store at -20℃, for extended storage, conserve at -20℃ or -80℃.
Notes:
 Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Referrences:
 [1] "Cloning of a T cell growth factor that interacts with the beta chain of the interleukin-2 receptor."
Grabstein K.H., Eisenman J., Shanebeck K., Rauch C., Srinivasan S., Fung V., Beers C., Richardson J., Schoenborn M.A., Ahdieh M., Johnson L., Alderson M.R., Watson J.D., Anderson D.M., Giri J.G.
Science 264:965-968(1994) [PubMed: 8178155] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM IL15-S48AA).
Tissue: Bone marrow.

[2] "Genomic sequence and chromosomal location of the human interleukin-15 gene (IL15)."
Krause H., Jandrig B., Wernicke C., Bulfone-Paus S., Pohl T., Diamantstein T.
Cytokine 8:667-674(1996) [PubMed: 8932977] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

[3] "Identification of a novel interleukin-15 (IL-15) transcript isoform generated by alternative splicing in human small cell lung cancer cell lines."
Meazza R., Verdiani S., Biassoni R., Coppolecchia M., Gaggero A., Orengo A.M., Colombo M.P., Azzarone B., Ferrini S.
Oncogene 12:2187-2192(1996) [PubMed: 8668345] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM IL15-S21AA).
Tissue: Lung cancer.

[4] "Generation of secretable and nonsecretable interleukin 15 isoforms through alternate usage of signal peptides."
Tagaya Y., Kurys G., Thies T.A., Losi J.M., Azimi N., Hanover J.A., Bamford R.N., Waldmann T.A.
Proc. Natl. Acad. Sci. U.S.A. 94:14444-14449(1997) [PubMed: 9405632] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM IL15-S21AA).
Tissue: Testis.

[5] "Expression of two IL-15 mRNA isoforms in human tumors does not correlate with secretion: role of different signal peptides."
Meazza R., Ferrini S.
Submitted (APR-1997) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].

AA sequence:
 NWVNVISDLKKIEDLIQSMHIDATLYTESDVHPSCKVTAMKCFLLELQVISLESGDASIHDTVENLIILA
NNSLSSNGNVTESGCKECEELEEKNIKEFLQSFVHIVQMFINTS
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