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Home > Recombinant Protein > Recombinant human Interleukin-4 protein
Product Name:

Recombinant human Interleukin-4 protein

Product Type:
 Recombinant Protein
Application:
 Immunogen，ELISA
Code:
 CSB-RP067374h
Relevance:
 Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes.
Mol. Weight:
 20 KD
Product Info:
 HIS-tagged
Purity:
 90%
Image:
Storage Buffer:
 6M guanidine hydrochloride, 20mM Tris
Storage:
 Store at -20℃, for extended storage, conserve at -20℃ or -80℃.
Notes:
 Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Referrences:
 [1] "Isolation and characterization of a human interleukin cDNA clone, homologous to mouse B-cell stimulatory factor 1, that expresses B-cell- and T-cell-stimulating activities."
Yokota T., Otsuka T., Mosmann T., Banchereau J., Defrance T., Blanchard D., de Vries J.E., Lee F., Arai K.
Proc. Natl. Acad. Sci. U.S.A. 83:5894-5898(1986) [PubMed: 3016727] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).

[2] "Complete nucleotide sequence of the chromosomal gene for human IL-4 and its expression."
Arai N., Nomura D., Villaret D., Malefijt R.D., Seiki M., Yoshida M., Minoshima S., Fukuyama R., Maekawa M., Kudoh J., Shimizu N., Yokota K., Abe E., Yokota T., Takebe Y., Arai K.
J. Immunol. 142:274-282(1989) [PubMed: 2535858] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

[3] "An alternatively spliced interleukin 4 form in lymphoid cells."
Klein S.C., Golverdingen J., Bouwens A.G.M., Tilanus M.G.J.
Immunogenetics 41:57-57(1995) [PubMed: 7806280] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2).
AA sequence:
 HKCDITLQEIIKTLNSLTEQKTLCTELTVTDIFAASKNTTEKETFCRAATVLRQFYSHHEKDTRCLGATA
QQFHRHKQLIRFLKRLDRNLWGLAGLNSCPVKEANQSTLENFLERLKTIMREKYSKCSS
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