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Home > Recombinant Protein > Recombinant human Heterogeneous nuclear ribonucleoprotein K protein
Product Name:

Recombinant human Heterogeneous nuclear ribonucleoprotein K protein

Product Type:
 Recombinant Protein
Application:
 Immunogen，ELISA
Code:
 CSB-RP025344h
Relevance:
 One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA.
Mol. Weight:
 78 KD
Product Info:
 GST tagged
Purity:
 90%
Image:
Storage Buffer:
 PBS buffer, 20mM GSH
Storage:
 Store at -20℃, for extended storage, conserve at -20℃ or -80℃.
Notes:
 Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Referrences:
 [1] "Characterization and primary structure of the poly(C)-binding heterogeneous nuclear ribonucleoprotein complex K protein."
Matunis M.J., Michael W.M., Dreyfuss G.
Mol. Cell. Biol. 12:164-171(1992) [PubMed: 1729596] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), SUBCELLULAR LOCATION.

[2] "Identification, molecular cloning, expression and chromosome mapping of a family of transformation upregulated hnRNP-K proteins derived by alternative splicing."
Dejgaard K., Leffers H., Rasmussen H.H., Madsen P., Kruse T.A., Gesser B., Nielsen H., Celis J.E.
J. Mol. Biol. 236:33-48(1994) [PubMed: 8107114] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), PHOSPHORYLATION.

[3] Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S., Ohara O., Nagase T., Kikuno R.F.
Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3).
Tissue: Brain.
AA sequence:
 TEQPEETFPNTETNGEFGKRPAEDMEEEQAFKRSRNTDEMVELRILLQSKNAGAVIGKGGKNIKALRTDY
NASVSVPDSSGPERILSISADIETIGEILKKIIPTLEEGLQLPSPTATSQLPLESDAVECLNYQHYKGSD
FDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIKIILDL
ISESPIKGRAQPYDPNFYDETYDYGGFTMMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRRDYDD
MSPRRGPPPPPPGRGGRGGSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVGFSADETWDSAIDTW
SPSEWQMAYEPQGGSGYDYSYAGGRGSYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIK
IDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQYADVEGF
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