Bovine Inhibin beta B chain(INHBB) ELISA kit

Unavailable
Code CSB-EL011720BO
See More Details
Product Type ELISA Kit
Size 96T,5×96T,10×96T
Uniprot No. P42917
Lead Time 7-14 working days
Abbreviation INHBB
Target Name inhibin, beta B
Alias MGC157939, Inhibin, beta-2|activin AB beta polypeptide|inhibin beta B subunit
Species Bos taurus (Bovine)
Detection Range Request Information
Sensitivity Request Information
Assay Time 1-5h
Sample Volume 50-100ul
Detection Wavelength 450 nm
Research Area Signal Transduction
Target Details The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion.
HGNC 6067
RGD 2913
MGI 96571
Still Have Questions? Leave a Message or Start an on-line Chat
Function Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
Subcellular Location Secreted
Protein Families TGF-beta family
Database Links

STRING: 9913.ENSBTAP00000042801

Pathway TGF-beta signaling pathway
Signaling pathways regulating pluripotency of stem cells

Related Products

INHBB Proteins

INHBB Proteins for Bos taurus (Bovine)

Most popular with customers

Newsletters

Get all the latest information on Events, Sales and Offers. Sign up for newsletter today.

Copyright © 2007-2018 www.cusabio.com CUSABIO TECHNOLOGY LLC All Rights Reserved.

Wait!

Join the 25,000 subscribers to get research hotpots, technical tips, latest information on events, sales and offers.

Sign up now!

We don't deal in spam.