Bovine Integrin alpha-2(ITGA2) ELISA kit

Unavailable
Code CSB-EL011864BO
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Product Type ELISA Kit
Size 96T,5×96T,10×96T
Uniprot No. P53710
Lead Time 5-7 working days
Abbreviation ITGA2
Protein Biological Process 1 Cell Adhesion
Target Name integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
Alias BR, CD49B, GPIa, VLA-2, VLAA2, integrin alpha 2|platelet antigen Br|platelet glycoprotein GPIa|platelet glycoprotein Ia|very late activation protein 2 receptor, alpha-2 subunit
Species Bos taurus (Bovine)
Protein Biological Process 3 Cell adhesion
Detection Range Request Information
Sensitivity Request Information
Assay Time 1-5h
Sample Volume 50-100ul
Detection Wavelength 450 nm
Research Area Signal Transduction
Target Details This gene product belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane glycoproteins composed of a distinct alpha chain and a common beta chain. They are found on a wide variety of cell types including, T cells, fibroblasts and platelets. Integrins are involved in cell adhesion and also participate in cell-surface mediated signalling.
HGNC 6137
RGD 621632
MGI 96600
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Function Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix.
Subcellular Location Membrane, Single-pass type I membrane protein
Protein Families Integrin alpha chain family
Database Links

STRING: 9913.ENSBTAP00000025685

UniGene: Bt.12761

Pathway PI3K-Akt signaling pathway
Focal adhesion
Regulation of actin cytoskeleton
Hematopoietic cell lineage

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