Guinea pig Apolipoprotein B (APOB) ELISA kit

Code CSB-EL001918GU
See More Details 24T ELISA kits trial application
Product Type ELISA Kit
Size 96T,5×96T,10×96T
Lead Time 3-5 working days
Protein Biological Process 2 Lipogenesis and lipometabolism
Abbreviation APOB
Protein Biological Process 1 Apolipoprotein
Target Name apolipoprotein B (including Ag(x) antigen) (APOB)
Alias FLDB, LDLCQ4, apoB-100|apoB-48|apolipoprotein B|apolipoprotein B48
Species Guinea Sus scrofa (Pig)
Protein Biological Process 3 Cholesterol metabolism
Sample Types serum, plasma, tissue homogenates
Detection Range 0.47 μg/mL-30 μg/mL
Sensitivity 0.11 μg/mL
Assay Time 1-5h
Sample Volume 50-100ul
Detection Wavelength 450 nm
Research Area Cardiovascular
Protocol may be improved. Please feel free to contact CUSABIO product specialist to obtain the latest version.
Assay Principle quantitative
Measurement Competitive
Target Details This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels.
HGNC 603
RGD 2129
MGI 88052
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