Guinea pig C-C motif chemokine 5(CCL5) ELISA kit

Instructions
Code CSB-EL004800GU
Size 96T,5×96T,10×96T
Trial Size 24T ELISA kits trial application
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Product Details

Target Name chemokine (C-C motif) ligand 5
Alternative Names CCL5 ELISA kit; SCYA5C-C motif chemokine 5 ELISA kit; SIS-delta ELISA kit; Small-inducible cytokine A5 ELISA kit; T-cell-specific protein RANTES ELISA kit
Abbreviation CCL5
Uniprot No. P97272
Species Cavia porcellus (Guinea pig)
Sample Types serum, plasma, tissue homogenates
Detection Range 0.156 ng/mL-10 ng/mL
Sensitivity 0.081 ng/mL
Assay Time 1-5h
Sample Volume 50-100ul
Detection Wavelength 450 nm
Research Area Immunology
Assay Principle quantitative
Measurement Sandwich
Troubleshooting
and FAQs
ELISA kit FAQs
Storage Store at 2-8°C. Please refer to protocol.
Lead Time 5-7 working days

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Target Data

Function Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells.
Gene References into Functions
  1. In the pathogenesis of allergic rhinitis, substance P induces expression of RANTES in nasal mucosa. PMID: 16570818
Subcellular Location Secreted
Protein Families Intercrine beta (chemokine CC) family
Database Links

STRING: 10141.ENSCPOP00000007949

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