Human Insulin-like growth factor-binding protein complex acid labile subunit(IGFALS) ELISA kit

Code CSB-EL011094HU
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Product Type ELISA Kit
Size 96T,5×96T,10×96T
Uniprot No. P35858
Lead Time 5-7 working days
Abbreviation IGFALS
Protein Biological Process 1 Cell Adhesion
Target Name insulin-like growth factor binding protein, acid labile subunit
Alias ALS, insulin-like growth factor binding protein complex acid labile chain
Species Homo sapiens (Human)
Protein Biological Process 3 Cell adhesion
Detection Range Request Information
Sensitivity Request Information
Assay Time 1-5h
Sample Volume 50-100ul
Detection Wavelength 450 nm
Research Area Others
Target Details This protein is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty. Three transcript variants encoding two different isoforms have been found for this gene.
HGNC 5468
RGD 68429
MGI 107973
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Function Involved in protein-protein interactions that result in protein complexes, receptor-ligand binding or cell adhesion.
Involvement in disease Acid-labile subunit deficiency (ACLSD)
Subcellular Location Secreted, extracellular space
Tissue Specificity Plasma.
Database Links

HGNC: 5468

OMIM: 601489

KEGG: hsa:3483

STRING: 9606.ENSP00000416683

UniGene: Hs.839

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