Human Protein S100-A3(S100A3) ELISA kit

Code CSB-EL020631HU
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Product Type ELISA Kit
Size 96T,5×96T,10×96T
Uniprot No. P33764
Lead Time 7-14 working days
Abbreviation S100A3
Target Name S100 calcium binding protein A3
Alias S100E, OTTHUMP00000032963|S100 calcium-binding protein A3
Species Homo sapiens (Human)
Detection Range Request Information
Sensitivity Request Information
Assay Time 1-5h
Sample Volume 50-100ul
Detection Wavelength 450 nm
Research Area Signal Transduction
Target Details This protein is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein has the highest content of cysteines of all S100 proteins, has a high affinity for Zinc, and is highly expressed in human hair cuticle. The precise function of this protein is unknown.
HGNC 10493
RGD 620260
MGI 1338849
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Function Binds both calcium and zinc. May be involved in calcium-dependent cuticle cell differentiation, hair shaft and hair cuticular barrier formation.
Subcellular Location Cytoplasm
Protein Families S-100 family
Tissue Specificity Skin specific, specifically expressed at the inner endocuticle of hair fibers.
Database Links

HGNC: 10493

OMIM: 176992

KEGG: hsa:6274

STRING: 9606.ENSP00000357701

UniGene: Hs.557609

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