Human Protein Wnt-7a(WNT7A) ELISA kit

Code CSB-EL026141HU
See More Details 24T ELISA kits trial application
Product Type ELISA Kit
Size 96T,5×96T,10×96T
Uniprot No. O00755
Lead Time 5-7 working days
Abbreviation WNT7A
Protein Biological Process 1 Signaling Pathway
Target Name wingless-type MMTV integration site family, member 7A
Alias , proto-oncogene Wnt7a protein
Species Homo sapiens (Human)
Protein Biological Process 3 Wnt signaling pathway
Detection Range Request Information
Sensitivity Request Information
Assay Time 1-5h
Sample Volume 50-100ul
Detection Wavelength 450 nm
Research Area Stem Cells
Protocol
Protocol may be improved. Please feel free to contact CUSABIO product specialist to obtain the latest version.
Target Details This gene is a member of the WNT gene family, which consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is involved in the development of the anterior-posterior axis in the female reproductive tract, and also plays a critical role in uterine smooth muscle pattering and maintenance of adult uterine function. Mutations in this gene are associated with Fuhrmann and Al-Awadi/Raas-Rothschild/Schinzel phocomelia syndromes.
HGNC 12786
RGD 69079
MGI 98961
References
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Function Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. Signaling by Wnt-7a allows sexually dimorphic development of the mullerian ducts (By similarity).
Involvement in disease Limb pelvis hypoplasia aplasia syndrome (LPHAS); Fuhrmann syndrome (FUHRS)
Subcellular Location Secreted, extracellular space, extracellular matrix
Protein Families Wnt family
Tissue Specificity Expression is restricted to placenta, kidney, testis, uterus, fetal lung, and fetal and adult brain.
Database Links

HGNC: 12786

OMIM: 228930

KEGG: hsa:7476

STRING: 9606.ENSP00000285018

UniGene: Hs.72290

Pathway Hippo signaling pathway
Melanogenesis
mTOR signaling pathway
Wnt signaling pathway
Signaling pathways regulating pluripotency of stem cells

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