Human Secretin ELISA Kit

Code CSB-E09017h
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Product Type ELISA Kit
Size 96T,5×96T,10×96T
Uniprot No. P09683
Lead Time 3-5 working days
Abbreviation SCT
Target Name secretin
Alias N/A
Species Homo sapiens (Human)
Sample Types serum, plasma
Detection Range 0.312 ng/mL-20 ng/mL
Sensitivity 0.078 ng/mL
Assay Time 1-5h
Sample Volume 50-100ul
Detection Wavelength 450 nm
Research Area Signal Transduction
Protocol
Protocol may be improved. Please feel free to contact CUSABIO product specialist to obtain the latest version.
Assay Principle quantitative
Measurement Sandwich
Target Details Secretin belongs to the glucagon family. This protein is an endocrine hormone and its major site of production is the endocrine S cells located in the proximal small intestinal mucosa. The release of active secretin is stimulated by either fatty acids or an acidic pH in the duodenum. This hormone stimulates the secretion of bicarbonate-rich pancreatic fluids and has also been shown to regulate the growth and development of the stomach, small intestine, and pancreas. Secretin deficiency has been implicated in autistic syndrome, suggesting that the hormone could have a neuroendocrine function in addition to its role in digestion.
HGNC 3755
RGD 1311915
MGI 2446089
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Function Stimulates formation of NaHCO(3)-rich pancreatic juice and secretion of NaHCO(3)-rich bile and inhibits HCl production by the stomach.
Subcellular Location Secreted
Protein Families Glucagon family
Database Links

HGNC: 10607

OMIM: 182099

KEGG: hsa:6343

STRING: 9606.ENSP00000176195

UniGene: Hs.632324

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