Human Tumor necrosis factor receptor superfamily member 19(TNFRSF19) ELISA kit

Unavailable
Code CSB-EL023976HU
See More Details 24T ELISA kits trial application
Product Type ELISA Kit
Size 96T,5×96T,10×96T
Uniprot No. Q9NS68
Lead Time 5-7 working days
Abbreviation TNFRSF19
Protein Biological Process 1 Apoptosis/Autophagy
Target Name tumor necrosis factor receptor superfamily, member 19
Alias TAJ, TAJ-alpha, TRADE, TROY, OTTHUMP00000018114|toxicity and JNK inducer
Species Homo sapiens (Human)
Protein Biological Process 3 Apoptosis
Detection Range Request Information
Sensitivity Request Information
Assay Time 1-5h
Sample Volume 50-100ul
Detection Wavelength 450 nm
Research Area Signal Transduction
Target Details This protein is a member of the TNF-receptor superfamily. This receptor is highly expressed during embryonic development. It has been shown to interact with TRAF family members, and to activate JNK signaling pathway when overexpressed in cells. This receptor is capable of inducing apoptosis by a caspase-independent mechanism, and it is thought to play an essential role in embryonic development. Alternatively spliced transcript variants encoding distinct isoforms have been described.
HGNC 11915
MGI 1352474
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Function Can mediate activation of JNK and NF-kappa-B. May promote caspase-independent cell death.
Subcellular Location Membrane, Single-pass type I membrane protein
Tissue Specificity Highly expressed in prostate. Detected at lower levels in thymus, spleen, testis, uterus, small intestine, colon and peripheral blood leukocytes.
Database Links

HGNC: 11915

OMIM: 606122

KEGG: hsa:55504

STRING: 9606.ENSP00000371693

UniGene: Hs.149168

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