Mouse Fibroblast growth factor 20(FGF20) ELISA kit

Instructions
Code CSB-EL008626MO
Size 96T,5×96T,10×96T
See More Details 24T ELISA kits trial application
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Product Details

Target Name fibroblast growth factor 20
Alternative Names Fgf20Fibroblast growth factor 20 ELISA kit; FGF-20 ELISA kit
Abbreviation FGF20
Uniprot No. Q9ESL9
Species Mus musculus (Mouse)
Sample Types serum, plasma, tissue homogenates
Detection Range 1600 pg/mL-25 pg/mL
Sensitivity 6.25 pg/mL
Assay Time 1-5h
Sample Volume 50-100ul
Detection Wavelength 450 nm
Research Area Signal Transduction
Troubleshooting
and FAQs
ELISA kit FAQs
Storage Store at 2-8°C. Please refer to protocol.
Lead Time 7-14 working days

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Target Data

Function Neurotrophic factor that regulates central nervous development and function.
Gene References into Functions
  1. Data show that Fibroblast Growth Factors (FGF) 9 and 20 regulate the number of cochlear progenitors. PMID: 25915623
  2. fibroblast growth factor 20 (Fgf20) is expressed in hair placodes and is induced by and functions downstream from epithelial ectodysplasin (Eda)/Edar and Wnt/beta-Catenin signaling to initiate formation of the underlying dermal condensation PMID: 23431057
  3. We hypothesized that Fgf20 plays a role in specification, amplification, or maintenance of Sox2 expression in prosensory progenitors of the developing mammalian cochlea. PMID: 22973011
  4. Fgf20 is a major downstream effector of ectodysplasin and affects ectodysplasin-regulated characteristics of tooth morphogenesis, including the number, size and shape of teeth. PMID: 22833125
  5. The data suggested that, at a minimum, Fgf9/20 and Bmp7 organize the nephron progenitor niche. FGF signaling likely regulates multiple important steps in the niche, including survival, proliferation, and competence. PMID: 22698282
  6. Data indicate that the viability and hearing loss in Fgf20 knockout mice suggest that FGF20 may also be a deafness-associated gene in humans. PMID: 22235191
  7. expression of FGF20 in calvarial and limb development PMID: 11900978
  8. Fgf20 is expressed at the right time and place to mediate sensory cell specification and is the likely activator/ligand of fibroblast growth factor (FGF) receptor 1 during cochlear development. PMID: 18524904

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Subcellular Location Secreted
Protein Families Heparin-binding growth factors family
Database Links

KEGG: mmu:80857

STRING: 10090.ENSMUSP00000034014

UniGene: Mm.425526

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