Mouse Soluble protein-100,S-100 ELISA Kit

Code CSB-E08068m
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Product Type ELISA Kit
Size 96T,5×96T,10×96T
Uniprot No. P56565
Lead Time 3-5 working days
Abbreviation S100A1
Target Name S100 calcium binding protein A1
Alias S100, S100-alpha, S100A, S100 alpha|S100 calcium-binding protein A1|S100 protein, alpha polypeptide
Species Mus musculus (Mouse)
Sample Types serum, plasma, tissue homogenates
Detection Range 3.12 ng/mL-200 ng/mL
Sensitivity 0.78 ng/mL
Assay Time 1-5h
Sample Volume 50-100ul
Detection Wavelength 450 nm
Research Area Signal Transduction
Protocol
Protocol may be improved. Please feel free to contact CUSABIO product specialist to obtain the latest version.
Assay Principle quantitative
Measurement Sandwich
Target Details This protein is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies.
HGNC 10486
RGD 3614
MGI 1338917
References
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Function Probably acts as a Ca(2+) signal transducer. In response to an increase in intracellular Ca(2+) levels, binds calcium which triggers a conformational change. This conformational change allows interaction of S1001A with specific target proteins, such as TPR-containing proteins, and the modulation of their activity.
Subcellular Location Cytoplasm
Protein Families S-100 family
Database Links

KEGG: mmu:20193

STRING: 10090.ENSMUSP00000058237

UniGene: Mm.24662

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