Mouse Troponin I, slow skeletal muscle(TNNI1) ELISA kit

Instructions
Code CSB-EL024011MO
Size 96T,5×96T,10×96T
See More Details 24T ELISA kits trial application
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Product Details

Target Name troponin I type 1 (skeletal, slow)
Alternative Names Tnni1 ELISA Kit; Troponin I ELISA Kit; slow skeletal muscle ELISA Kit; Troponin I ELISA Kit; slow-twitch isoform ELISA Kit
Abbreviation TNNI1
Uniprot No. Q9WUZ5
Species Mus musculus (Mouse)
Detection Range Request Information
Sensitivity Request Information
Assay Time 1-5h
Sample Volume 50-100ul
Detection Wavelength 450 nm
Research Area Signal Transduction
Troubleshooting
and FAQs
ELISA kit FAQs
Storage Store at 2-8°C. Please refer to protocol.
Lead Time 7-14 working days

Target Data

Function Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
Gene References into Functions
  1. data demonstrate that thyroid hormone can alter the time course of ssTnI gene expression in cultured cardiac myocytes and TnI gene regulation is also controlled by some unknown programmed events inside of cardiac myocytes PMID: 15695175
  2. a localized N-terminal region of TnI comprised of amino acids 33-80, which interacts with C-terminal regions of cTnC and cTnT, is of particular significance in transducing signaling of thin filament activation by strong cross-bridges PMID: 17099250
  3. K+-depolarization increased Tnni1 and Acta1 mRNA levels in both differentiated C2C12 and rat skeletal muscle cells in primary culture PMID: 17146758
  4. the up-stream domain ( approximately 1,800 bp) of mouse fetal TnI gene is been cloned and characterized PMID: 18357515
  5. Phosphorylation of troponin I was significantly reduced in Galphaq-overexpressing mice compared to wild type. PMID: 18473122

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Protein Families Troponin I family
Database Links

KEGG: mmu:21952

STRING: 10090.ENSMUSP00000121343

UniGene: Mm.44379

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