Mouse Tumor necrosis factor receptor superfamily member 4(TNFRSF4) ELISA kit

Code CSB-EL023981MO
See More Details 24T ELISA kits trial application
Product Type ELISA Kit
Size 96T,5×96T,10×96T
Uniprot No. P47741
Lead Time 7-14 working days
Abbreviation TNFRSF4
Target Name tumor necrosis factor receptor superfamily, member 4
Alias RP5-902P8.3, ACT35, CD134, OX40, TXGP1L, ATC35 antigen|CD134 antigen|OX40 antigen|OX40 cell surface antigen|OX40 homologue|lymphoid activation antigene ACT35|tax-transcriptionally activated glycopro
Species Mus musculus (Mouse)
Detection Range Request Information
Sensitivity Request Information
Assay Time 1-5h
Sample Volume 50-100ul
Detection Wavelength 450 nm
Research Area Others
Target Details This protein is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation.
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Function Receptor for TNFSF4/OX40L/GP34. Is a costimulatory molecule implicated in long-term T-cell immunity (By similarity).
Subcellular Location Membrane, Single-pass type I membrane protein
Database Links

KEGG: mmu:22163

STRING: 10090.ENSMUSP00000030952

UniGene: Mm.13885

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