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| Code | CSB-EL004949MO |
| Size | 96T,5×96T,10×96T |
| Price | Request a Quote or Start an on-line Chat |
| Trial Size |
24T ELISA Kit Trial Size (Only USD$150/ kit) * The sample kit cost can be deducted from your subsequent orders of 96T full size kits of the same analyte at 1/5 per kit, until depleted in 6 months. Apply now |
The ELISA Kit is designed for quantitatively measuring mouse CD6 levels in samples, including serum, plasma, or tissue homogenates. It uses the sandwich enzyme immunoassay technique in combination with the enzyme-substrate chromogenic reaction to quantify the analyte in the sample. The color develops positively to the amount of CD6 in samples. The color intensity is measured at 450 nm via a microplate reader.
CD6 is a T-cell costimulatory receptor implicated in the pathogenesis of multiple autoimmune and inflammatory diseases. CD6 is mainly expressed on CD4 T cells and promotes immune synapse formation, T-cell activation, and T-cell migration through interaction with its ligand ALCAM/CD166. The CD6-ALCAM pathway modulates T cell activation, differentiation, and trafficking and thus plays an integral role in inflammation and autoimmunity. CD6 has been involved in numerous inflammatory and autoimmune diseases, including psoriasis, multiple sclerosis, rheumatoid arthritis, graft versus host disease, Sjögren’s syndrome, and inflammatory bowel disease.
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