Mouse fibroblast growth factor 9 (glia-activating factor) (FGF9) ELISA kit

Code CSB-E07335m
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Product Type ELISA Kit
Size 96T,5×96T,10×96T
Uniprot No. P54130
Lead Time 3-5 working days
Abbreviation FGF9
Protein Biological Process 1 Developmental Protein
Target Name fibroblast growth factor 9 (glia-activating factor)
Alias GAF, HBFG-9, MGC119914, MGC119915, SYNS3, fibroblast growth factor 9
Species Mus musculus (Mouse)
Protein Biological Process 3 Differentiation
Sample Types serum, plasma, tissue homogenates
Detection Range 400 pg/mL-6.25 pg/mL
Sensitivity 1.56 pg/mL
Assay Time 1-5h
Sample Volume 50-100ul
Detection Wavelength 450 nm
Research Area Signal Transduction
Target Details This protein is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein was isolated as a secreted factor that exhibits a growth-stimulating effect on cultured glial cells. In nervous system, this protein is produced mainly by neurons and may be important for glial cell development. Expression of the mouse homolog of this gene was found to be dependent on Sonic hedgehog (Shh) signaling. Mice lacking the homolog gene displayed a male-to-female sex reversal phenotype, which suggested a role in testicular embryogenesis.
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Function Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. May have a role in glial cell growth and differentiation during development, gliosis during repair and regeneration of brain tissue after damage, differentiation and survival of neuronal cells, and growth stimulation of glial tumors.
Subcellular Location Secreted
Protein Families Heparin-binding growth factors family
Database Links

KEGG: mmu:14180

STRING: 10090.ENSMUSP00000022545

UniGene: Mm.8846

Pathway MAPK signaling pathway
PI3K-Akt signaling pathway
Regulation of actin cytoskeleton
Ras signaling pathway
Rap1 signaling pathway

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