Rat Agouti-signaling protein(ASIP) ELISA kit

Code CSB-EL002212RA
Size 96T,5×96T,10×96T
See More Details 24T ELISA kits trial application
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Product Details

Target Name agouti signaling protein, nonagouti homolog (mouse)
Alternative Names Asip ELISA Kit; A ELISA Kit; Agouti-signaling protein ELISA Kit; ASP ELISA Kit; Agouti switch protein ELISA Kit
Abbreviation ASIP
Uniprot No. Q99JA2
Species Rattus norvegicus (Rat)
Sample Types serum, plasma, tissue homogenates
Detection Range 31.25 pg/mL-2000 pg/mL
Sensitivity 7.81 pg/mL
Assay Time 1-5h
Sample Volume 50-100ul
Detection Wavelength 450 nm
Research Area Signal Transduction
and FAQs
Storage Store at 2-8°C. Please refer to protocol.
Lead Time 7-14 working days

Target Data

Function Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment).
Gene References into Functions
  1. Aggressive offspring is more sensitive to the mother's methyl-containing diet: the percentage of animals that are darker than control rats is higher among aggressive animals than among tame ones PMID: 19534427
Subcellular Location Secreted
Database Links

KEGG: rno:24152

UniGene: Rn.205372

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