Rat Hepatocyte nuclear factor 1-alpha(HNF1A) ELISA kit

Code CSB-EL010592RA
See More Details 24T ELISA kits trial application
Product Type ELISA Kit
Size 96T,5×96T,10×96T
Uniprot No. P15257
Lead Time 5-7 working days
Abbreviation HNF1A
Protein Biological Process 1 Transcription/Transcription regulation
Target Name HNF1 homeobox A
Alias HNF1, LFB1, MODY3, TCF1, albumin proximal factor|hepatic nuclear factor 1|hepatic nuclear factor-1-alpha|interferon production regulator factor|transcription factor 1, hepatic|transcription factor 1
Species Rattus norvegicus (Rat)
Protein Biological Process 3 Transcription
Detection Range Request Information
Sensitivity Request Information
Assay Time 1-5h
Sample Volume 50-100ul
Detection Wavelength 450 nm
Research Area Signal Transduction
Target Details This protein is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5 -GTTAATNATTAAC-3 . Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas.
References
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Function Transcriptional activator that regulates the tissue specific expression of multiple genes, especially in pancreatic islet cells and in liver. Required for the expression of several liver specific genes. Binds to the inverted palindrome 5'-GTTAATNATTAAC-3'.
Subcellular Location Nucleus
Protein Families HNF1 homeobox family
Tissue Specificity Liver.
Database Links

KEGG: rno:24817

STRING: 10116.ENSRNOP00000001565

UniGene: Rn.9660

Pathway Signaling pathways regulating pluripotency of stem cells

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