Rat Insulin-like growth factor-binding protein complex acid labile subunit(IGFALS) ELISA kit

Code CSB-EL011094RA
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Product Type ELISA Kit
Size 96T,5×96T,10×96T
Uniprot No. P35859
Lead Time 5-7 working days
Abbreviation IGFALS
Protein Biological Process 1 Cell Adhesion
Target Name insulin-like growth factor binding protein, acid labile subunit
Alias ALS, insulin-like growth factor binding protein complex acid labile chain
Species Rattus norvegicus (Rat)
Protein Biological Process 3 Cell adhesion
Sample Types serum, plasma,tissue homogenates
Detection Range 3.12 ng/mL-200 ng/mL
Sensitivity 0.78 ng/mL
Assay Time 1-5h
Sample Volume 50-100ul
Detection Wavelength 450 nm
Research Area Others
Protocol
Protocol may be improved. Please feel free to contact CUSABIO product specialist to obtain the latest version.
Assay Principle quantitative
Measurement Sandwich
Target Details This protein is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty. Three transcript variants encoding two different isoforms have been found for this gene.
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Function May have an important role in regulating the access of circulating IGFs to the tissues.
Subcellular Location Secreted, extracellular space
Tissue Specificity Brain, kidney, lung, heart, spleen, muscle and liver.
Database Links

KEGG: rno:79438

STRING: 10116.ENSRNOP00000020233

UniGene: Rn.7327

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