Rat Lysosome-associated membrane glycoprotein 1(LAMP1) ELISA kit

Instructions
Code CSB-EL012738RA
Size 96T,5×96T,10×96T
See More Details 24T ELISA kits trial application
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Product Details

Target Name lysosomal-associated membrane protein 1
Alternative Names Lamp1 ELISA Kit; Lamp-1Lysosome-associated membrane glycoprotein 1 ELISA Kit; LAMP-1 ELISA Kit; Lysosome-associated membrane protein 1 ELISA Kit; 120 kDa lysosomal membrane glycoprotein ELISA Kit; LGP-120 ELISA Kit; CD107 antigen-like family member A ELISA Kit; CD antigen CD107a ELISA Kit
Abbreviation LAMP1
Uniprot No. P14562
Species Rattus norvegicus (Rat)
Sample Types serum, plasma,tissue homogenates
Detection Range 125 pg/mL-8000 pg/mL
Sensitivity 31.25 pg/mL
Assay Time 1-5h
Sample Volume 50-100ul
Detection Wavelength 450 nm
Research Area Metabolism
Assay Principle quantitative
Measurement Sandwich
Troubleshooting
and FAQs
ELISA kit FAQs
Storage Store at 2-8°C. Please refer to protocol.
Lead Time 7-14 working days

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Target Data

Function Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis.
Gene References into Functions
  1. dihydrolipoic acid (DHLA) treatment improved neurofunction and alleviated inflammation through the lysosome-associated membrane protein-1/CaMKII/TAK1 pathway in early brain injury after subarachnoid hemorrhage (SAH). DHLA may provide a promising treatment to alleviate early brain injury after SAH. PMID: 29273596
  2. Here, we identify lamellar inclusions as the subcellular site of lipid accumulation in neurons, we uncover a vicious cycle of cholesterol synthesis and accretion, which may cause gradual neurodegeneration, and we reveal how beta-cyclodextrin, a potential therapeutic drug, reverts these changes. Our study provides new mechanistic insight in NPC disease and uncovers new targets for therapeutic approaches. PMID: 27466344
  3. conclude that status epilepticus not only increased autophagosomal abundance, but also lysosomal activities and a massive accumulation of LAMP1 in axons of dentate gyrus. This could support the hypothesis that the marked increased autophagosomal abundance in cytosol reflects an increase in the autophagic activity more than an inhibition of autophagosomal clearance PMID: 26329516
Subcellular Location Cell membrane, Single-pass type I membrane protein, Endosome membrane, Single-pass type I membrane protein, Lysosome membrane, Single-pass type I membrane protein, Late endosome
Protein Families LAMP family
Database Links

KEGG: rno:25328

STRING: 10116.ENSRNOP00000026580

UniGene: Rn.40177

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