Rat Ornithine decarboxylase(ODC1) ELISA kit

Code CSB-EL016269RA
See More Details 24T ELISA kits trial application
Product Type ELISA Kit
Size 96T,5×96T,10×96T
Uniprot No. P09057
Lead Time 5-7 working days
Protein Biological Process 2 biogenic amine biosynthesis and metabolism
Abbreviation ODC1
Protein Biological Process 1 Biosynthesis/Metabolism
Target Name ornithine decarboxylase 1
Alias ODC, OTTHUMP00000200387
Species Rattus norvegicus (Rat)
Protein Biological Process 3 Polyamine biosynthesis
Sample Types serum, plasma, tissue homogenates, cell lysates
Detection Range 93.75 pg/mL-6000 pg/mL
Sensitivity 23.43 pg/mL
Assay Time 1-5h
Sample Volume 50-100ul
Detection Wavelength 450 nm
Research Area Metabolism
Protocol
Protocol may be improved. Please feel free to contact CUSABIO product specialist to obtain the latest version.
Assay Principle quantitative
Measurement Sandwich
Target Details This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter.
References
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Function Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine. Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis.
Protein Families Orn/Lys/Arg decarboxylase class-II family
Database Links

KEGG: rno:24609

STRING: 10116.ENSRNOP00000007259

UniGene: Rn.874

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