Name: AATF Antibody, Biotin conjugated
Brand: CUSABIO
SKU: CSB-PA05264D0Rb

Product Details

Full Product Name	Rabbit anti-Homo sapiens (Human) AATF Polyclonal antibody
Uniprot No.	Q9NY61
Target Names	AATF
Alternative Names	Protein AATF (Apoptosis-antagonizing transcription factor) (Rb-binding protein Che-1), AATF, CHE1 DED
Raised in	Rabbit
Species Reactivity	Human
Immunogen	Recombinant Human Protein AATF protein (6-294AA)
Immunogen Species	Homo sapiens (Human)
Conjugate	Biotin
Clonality	Polyclonal
Isotype	IgG
Purification Method	>95%, Protein G purified
Concentration	It differs from different batches. Please contact us to confirm it.
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form	Liquid
Tested Applications	ELISA
Protocols	ELISA Protocol
Troubleshooting and FAQs	Antibody FAQs
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time	Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Still Have Questions?	Leave a Message or Start an on-line Chat

Target Data

Function	May function as a general inhibitor of the histone deacetylase HDAC1. Binding to the pocket region of RB1 may displace HDAC1 from RB1/E2F complexes, leading to activation of E2F target genes and cell cycle progression. Conversely, displacement of HDAC1 from SP1 bound to the CDKN1A promoter leads to increased expression of this CDK inhibitor and blocks cell cycle progression. Also antagonizes PAWR mediated induction of aberrant amyloid peptide production in Alzheimer disease (presenile and senile dementia), although the molecular basis for this phenomenon has not been described to date.
Subcellular Location	Nucleus, nucleolus
Protein Families	AATF family
Tissue Specificity	Ubiquitously expressed. Expressed at high levels in brain, heart, kidney, placenta and thymus.
Database Links	HGNC: 19235 OMIM: 608463 KEGG: hsa:26574 STRING: 9606.ENSP00000225402 UniGene: Hs.195740

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AATF Antibody, Biotin conjugated

Code	CSB-PA05264D0Rb
Size	US$299