AGPAT3 Antibody, FITC conjugated

Code CSB-PA865125LC01HU
Size US$299
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Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) AGPAT3 Polyclonal antibody
Uniprot No. Q9NRZ7
Target Names AGPAT3
Alternative Names 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma antibody; 1-acylglycerol-3-phosphate O-acyltransferase 3 antibody; 1-AGP acyltransferase 3 antibody; 1-AGPAT 3 antibody; acyltransferase gamma antibody; AGPAT3 antibody; LPAAT-gamma antibody; Lysophosphatidic acid acyltransferase gamma antibody; PLCC_HUMAN antibody; UNQ759/PRO1490 antibody
Raised in Rabbit
Species Reactivity Human
Immunogen Recombinant Human 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma protein (148-304AA)
Immunogen Species Homo sapiens (Human)
Conjugate FITC
Clonality Polyclonal
Isotype IgG
Purification Method >95%, Protein G purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form Liquid
Tested Applications ELISA
Protocols ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Target Data

Function Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Acts on LPA containing saturated or unsaturated fatty acids C16
Gene References into Functions
  1. The data is consistent with a structural arrangement in which motif I is located in the cytoplasm and motif II is in the endoplasmic reticulum and Golgi lumen, suggesting a different model for AGPAT3/LPAAT3's enzymatic mechanism. PMID: 20537980
  2. Of the two well conserved acyltransferase motifs, NHX(4)D is present in AGPAT8, whereas arginine in the EGTR motif is substituted by aspartate. PMID: 16620771
  3. Results report the identification of an integral membrane lysophosphatidic acid-specific acyltransferase, LPAAT3, which regulates Golgi membrane tubule formation, trafficking, and structure by altering phospholipids and lysophospholipids. PMID: 19635840
Subcellular Location Endoplasmic reticulum membrane, Multi-pass membrane protein, Nucleus envelope
Protein Families 1-acyl-sn-glycerol-3-phosphate acyltransferase family
Tissue Specificity Widely expressed with highest levels in testis, pancreas and kidney, followed by spleen, lung, adipose tissue and liver.
Database Links

HGNC: 326

OMIM: 614794

KEGG: hsa:56894

STRING: 9606.ENSP00000291572

UniGene: Hs.248785

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