AHI1 Antibody, Biotin conjugated

Datasheet
Code CSB-PA836642LD01HU
Size US$299
Uniprot No. Q8N157
Protocols ELISA Protocol
Immunogen Recombinant Human Jouberin protein (1-213AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance Involved in vesicle trafficking and required for ciliogenesis, formation of primary non-motile cilium, and recruitment of RAB8A to the basal body of primary cilium. Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Involved in neuronal differentiation.
Form Liquid
Conjugate Biotin
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1), AHI1
Immunogen Species Homo sapiens (Human)
Research Area Cell Biology
Target Names AHI1
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Involved in vesicle trafficking and required for ciliogenesis, formation of primary non-motile cilium, and recruitment of RAB8A to the basal body of primary cilium. Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Involved in neuronal differentiation.
Involvement in disease Joubert syndrome 3 (JBTS3)
Subcellular Location Cytoplasm, cytoskeleton, cilium basal body, Cell junction, adherens junction, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole
Tissue Specificity Highly expressed in the most primitive normal hematopoietic cells. Expressed in brain, particularly in neurons that give rise to the crossing axons of the corticospinal tract and superior cerebellar peduncles. Expressed in kidney (renal collecting duct ce
Database Links

HGNC: 21575

OMIM: 608629

KEGG: hsa:54806

STRING: 9606.ENSP00000265602

UniGene: Hs.386684

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