Name: ARPC2 Antibody, FITC conjugated
Brand: CUSABIO
SKU: CSB-PA03365C0Rb

Product Details

Full Product Name	Rabbit anti-Homo sapiens (Human) ARPC2 Polyclonal antibody
Uniprot No.	O15144
Target Names	ARPC2
Alternative Names	Actin related protein 2/3 complex subunit 2 34kDa antibody; Actin related protein 2/3 complex subunit 2 antibody; Actin-related protein 2/3 complex subunit 2 antibody; ARC 34 antibody; ARC34 antibody; Arp2/3 complex 34 kDa subunit antibody; ARP2/3 protein compex subunit 34 antibody; ARPC 2 antibody; Arpc2 antibody; ARPC2_HUMAN antibody; p34 Arc antibody; p34-ARC antibody; p34Arc antibody; PNAS 139 antibody; PNAS139 antibody; PRO 2446 antibody; PRO2446 antibody
Raised in	Rabbit
Species Reactivity	Human
Immunogen	Recombinant Human Actin-related protein 2/3 complex subunit 2 protein (1-250AA)
Immunogen Species	Homo sapiens (Human)
Conjugate	FITC
Clonality	Polyclonal
Isotype	IgG
Purification Method	>95%, Protein G purified
Concentration	It differs from different batches. Please contact us to confirm it.
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form	Liquid
Tested Applications	ELISA
Protocols	ELISA Protocol
Troubleshooting and FAQs	Antibody FAQs
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time	Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Related Products

Customer Reviews and Q&A

■ Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Earn $30 Amazon Card or 20μL/μg CUSABIO Trial Size Antibody. Details of rewards >>

Target Data

Function	Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.
Gene References into Functions	In the association analysis of 110 gastric cancer tissues, ARPC2 showed significant associations with large tumor size, lymph node invasion, and high tumor stage. In addition, ARPC2-positive patients exhibited lower RFS and OS rates compared with ARPC2-negative patients. We thus identify that ARPC2 plays an aneretic role in human gastric cancer and provided a new target for gastric cancer therapy. PMID: 28694563 Downregulation of the ARP2/3 complex signaling pathway, a common final pathway for multiple signaling cascades that regulate the actin cytoskeleton, would compromise the structural stability of spines, leading to their loss. In concert with findings from deletion of the ARP2/3 complex in mice, these findings support the idea that spine deficits in the DLPFC may contribute to subcortical hyperdopaminergia in schizophrenia. PMID: 27523502 Recent reports now demonstrate a novel aspect of the ARP2/3 complex and the nucleating-promoting factors in the maintenance of endothelial barrier function and junction remodeling of established endothelial cell junctions. PMID: 24621569 FOXF1 repressed cell growth and expression of collagen-1 and actin-related protein 2/3 complex, subunit 2. PMID: 25260753 The Arp2/3 complex is recruited to invading Rickettsia parkeri and is required for efficient invasion. PMID: 22188208 Filopodia initiation: focus on the Arp2/3 complex and formins PMID: 21975549 WASH is a bimodular protein and a component of the BLOC-1 complex in which the C terminus is involved in Arp2/3-mediated actin nucleation, whereas the N-terminal portion is required for its regulation and localization in the cells PMID: 20308062 The actin-related protein 2 accumulated in punctate structures that formed an extensivenetwork in a region corresponding to the postition of the Golgi complex. PMID: 15793564 Compared with controls, actin-related protein 2/3 level was markedly increased in brains of intractable epilepsy patients. PMID: 18708039 These findings strongly suggest that defective IL10 function is central to the pathogenesis of the ulcerative colitis subtype of inflammatory bowel disease. PMID: 18836448 Show More Hide All
Subcellular Location	Cytoplasm, cytoskeleton, Cell projection, Cell junction, synapse, synaptosome
Protein Families	ARPC2 family
Database Links	HGNC: 705 OMIM: 604224 KEGG: hsa:10109 STRING: 9606.ENSP00000295685 UniGene: Hs.529303

CloseMessage

Product >> Product Name：
Product >> Code：
Product >> Size：
Name： *
Email： *
Phone：
We recommend you to leave your phone number because occasionally our emails get flagged by spam filters. We would not disclose any of your private information to any third party.
Question/Comment： *
Your Region： *
Country State：
I'd like to receive email newsletters from Cusabio

Yes

No
How do you know CUSABIO?

Email

Distributor

Search engine

Advertisement

Others
Check Code：

Code	CSB-PA03365C0Rb
Size	US$299
Have Questions?	Leave a Message or Start an on-line Chat