ARPC3 Antibody, HRP conjugated

Datasheet

Code	CSB-PA03324B0Rb
Size	US$299
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Product Details

Full Product Name	Rabbit anti-Homo sapiens (Human) ARPC3 Polyclonal antibody
Uniprot No.	O15145
Target Names	ARPC3
Alternative Names	ARPC3 antibody; ARC21Actin-related protein 2/3 complex subunit 3 antibody; Arp2/3 complex 21 kDa subunit antibody; p21-ARC antibody
Raised in	Rabbit
Species Reactivity	Human
Immunogen	Recombinant Human Actin-related protein 2/3 complex subunit 3 protein (2-175AA)
Immunogen Species	Homo sapiens (Human)
Conjugate	HRP
Clonality	Polyclonal
Isotype	IgG
Purification Method	>95%, Protein G purified
Concentration	It differs from different batches. Please contact us to confirm it.
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form	Liquid
Tested Applications	ELISA
Protocols	ELISA Protocol
Troubleshooting and FAQs	Antibody FAQs
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time	Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Function (From Uniprot)	Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
Gene References into Functions	Cancer cell motility mediated by the actin-related protein 2/3 complex (Arp2/3) is required for vessel co-option in liver metastases in vivo. PMID: 27748747 genetic association study in population in Canada: Data suggest that an SNP in the promoter region of ARPC3 (CpG-SNP rs3759384 C>T) is associated with metabolic syndrome complicated by severe abdominal obesity and hypertriglyceridemia in the population studied. PMID: 27055012 Endogenous Nogo-B, which may exert its effects through ARPC 2/3 and MYL-9, is necessary for the migration and contraction of airway smooth muscle cells. PMID: 21251247 The actin-related protein 3 structures were more visible with anti-p34Arc monoclonal antibody. PMID: 15793564
Subcellular Location	Cytoplasm, cytoskeleton, Cell projection
Protein Families	ARPC3 family
Database Links	HGNC: 706 OMIM: 604225 KEGG: hsa:10094 STRING: 9606.ENSP00000228825 UniGene: Hs.524741

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