Name: B4GAT1 Antibody, HRP conjugated
Brand: CUSABIO
SKU: CSB-PA002499EB01HU

Product Details

Full Product Name	Rabbit anti-Homo sapiens (Human) B4GAT1 Polyclonal antibody
Uniprot No.	O43505
Target Names	B4GAT1
Alternative Names	3-N-acetylglucosaminyltransferase 1 antibody; 3-N-acetylglucosaminyltransferase antibody; B3GN-T1 antibody; B3GN1_HUMAN antibody; B3GNT1 antibody; B3GNT6 antibody; beta-1,3-N-acetylglucosaminyltransferase bGnT-6 antibody; BETA3GNTI antibody; I-beta-1 antibody; i-beta-1,3-N-acetylglucosaminyltransferase antibody; iGAT antibody; iGnT antibody; N-acetyllactosaminide beta-1 antibody; N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase antibody; OTTHUMP00000235058 antibody; Poly-N-acetyllactosamine extension enzyme antibody; UDP-GlcNAc:betaGal beta-1 antibody; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1 antibody; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 antibody
Raised in	Rabbit
Species Reactivity	Human
Immunogen	Recombinant Human Beta-1,4-glucuronyltransferase 1 protein (161-415AA)
Immunogen Species	Homo sapiens (Human)
Conjugate	HRP
Clonality	Polyclonal
Isotype	IgG
Purification Method	>95%, Protein G purified
Concentration	It differs from different batches. Please contact us to confirm it.
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form	Liquid
Tested Applications	ELISA
Protocols	ELISA Protocol
Troubleshooting and FAQs	Antibody FAQs
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time	Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Data

Function	Beta-1,4-glucuronyltransferase involved in O-mannosylation of alpha-dystroglycan (DAG1). Transfers a glucuronic acid (GlcA) residue onto a xylose (Xyl) acceptor to produce the glucuronyl-beta-1,4-xylose-beta disaccharide primer, which is further elongated by LARGE1, during synthesis of phosphorylated O-mannosyl glycan
Gene References into Functions	B4GAT1 is involved in the initiation of the LARGE-dependent repeating disaccharide that is necessary for extracellular matrix protein binding to O-mannosylated alpha-dystroglycan. PMID: 25279697 report describes the first truncating mutation in B3GNT1 and confirms that this gene, which plays a role in alphaDG glycosylation, is a bona fide disease gene in Walker-Warburg syndrome PMID: 23877401 These functional studies identify an important role of B3GNT1 in the synthesis of the uncharacterized laminin-binding glycan of alpha-dystroglycan and implicate B3GNT1 as a novel causative gene for Walker-Warburg syndrome. PMID: 23359570 These results demonstrate that B3GNT1 and B4GALT1 physically associate in vitro and in cultured cells, providing insight into possible mechanisms for regulation of polyLacNAc production. PMID: 19261593 These results identify a previously undescribed role of carbohydrate-dependent cell-basement membrane interaction in tumor suppression and its control by beta3GnT1 and LARGE. PMID: 19587235 Show More Hide All
Involvement in disease	Muscular dystrophy-dystroglycanopathy congenital with brain and eye anomalies A13 (MDDGA13)
Subcellular Location	Golgi apparatus membrane, Single-pass type II membrane protein
Protein Families	Glycosyltransferase 49 family
Tissue Specificity	In the adult, highly expressed in heart, brain, skeletal muscle and kidney and to a lesser extent in placenta, pancreas, spleen, prostate, testis, ovary, small intestine and colon. Very weak expression in lung, liver, thymus and peripheral blood leukocyte
Database Links	HGNC: 15685 OMIM: 605517 KEGG: hsa:11041 STRING: 9606.ENSP00000309096 UniGene: Hs.8526

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Code	CSB-PA002499EB01HU
Size	US$299
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B4GAT1 Antibody, HRP conjugated

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