BACH2 Antibody, HRP conjugated

Datasheet
Code CSB-PA883639LB01HU
Size US$299
Uniprot No. Q9BYV9
Immunogen Recombinant Human Transcription regulator protein BACH2 protein (136-235AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance Transcriptional regulator that acts as repressor or activator (By similarity). Binds to Maf recognition elements (MARE) (By similarity). Plays an important role in coordinating transcription activation and repression by MAFK (By similarity). Induces apoptosis in response to oxidative stress through repression of the antiapoptotic factor HMOX1 (PubMed:17018862). Positively regulates the nuclear import of actin (By similarity).
Form Liquid
Conjugate HRP
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Transcription regulator protein BACH2 (BTB and CNC homolog 2), BACH2
Immunogen Species Homo sapiens (Human)
Protocols ELISA Protocol
Research Area Immunology
Target Names BACH2
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Transcriptional regulator that acts as repressor or activator (By similarity). Binds to Maf recognition elements (MARE) (By similarity). Plays an important role in coordinating transcription activation and repression by MAFK (By similarity). Induces apoptosis in response to oxidative stress through repression of the antiapoptotic factor HMOX1
Subcellular Location Cytoplasm, Nucleus
Protein Families BZIP family, CNC subfamily
Tissue Specificity B-cell specific.
Database Links

HGNC: 14078

OMIM: 605394

KEGG: hsa:60468

STRING: 9606.ENSP00000257749

UniGene: Hs.269764

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