BCL2L1 Antibody

Datasheet
Code CSB-PA002613KA01HU
Size US$398
Image
  • Western blot analysis of extracts of K562 cells, using Bcl-xL antibody.
  • Immunohistochemistry of paraffin-embedded Colon cancer using Bcl-xL Antibody.

Product Details

Uniprot No. Q07817
Target Names BCL2L1
Alternative Names BCL2L1;BCL-XL/S;BCL2L;BCLX;Bcl-X;DKFZp781P2092;bcl-xL;bcl-xS ;BCLXS
Raised in Rabbit
Species Reactivity Human,Mouse,Rat
Immunogen Recombinant protein of Human BCL2L1
Immunogen Species Homo sapiens (Human)
Isotype IgG
Purification Method Affinity purification
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Store at -20°C or -80°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Tested Applications ELISA,WB,IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:50-1:200
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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Target Data

Function Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis.; FUNCTION
Subcellular Location Isoform Bcl-X(L): Mitochondrion inner membrane, Mitochondrion outer membrane, Mitochondrion matrix, Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane, Cytoplasm, cytosol, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, Nucleus membrane, Single-pass membrane protein, Cytoplasmic side
Protein Families Bcl-2 family
Tissue Specificity Bcl-X(S) is expressed at high levels in cells that undergo a high rate of turnover, such as developing lymphocytes. In contrast, Bcl-X(L) is found in tissues containing long-lived postmitotic cells, such as adult brain.
Database Links

HGNC: 992

OMIM: 600039

KEGG: hsa:598

STRING: 9606.ENSP00000302564

UniGene: Hs.516966

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