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| Code | CSB-PA755911LD01HU |
| Size | US$299 |
| Uniprot No. | Q7RTS1 |
| Protocols | ELISA Protocol |
| Immunogen | Recombinant Human Class A basic helix-loop-helix protein 15 protein (2-72AA) |
| Raised in | Rabbit |
| Species Reactivity | Human |
| Tested Applications | ELISA |
| Relevance | Plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5'-CANNTG-3' (By similarity). |
| Form | Liquid |
| Conjugate | Biotin |
| Storage Buffer | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method | >95%, Protein G purified |
| Isotype | IgG |
| Clonality | Polyclonal |
| Alias | Class A basic helix-loop-helix protein 15 (bHLHa15) (Class B basic helix-loop-helix protein 8) (bHLHb8) (Muscle, intestine and stomach expression 1) (MIST-1), BHLHA15, BHLHB8 MIST1 |
| Immunogen Species | Homo sapiens (Human) |
| Research Area | Epigenetics and Nuclear Signaling |
| Target Names | BHLHA15 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Still Have Questions? | Leave a Message or Start an on-line Chat |
| Function | Plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5'-CANNTG-3' (By similarity). |
| Subcellular Location | Nucleus |
| Tissue Specificity | Expressed in brain, liver, spleen and skeletal muscle. |
| Database Links |
HGNC: 22265 OMIM: 608606 KEGG: hsa:168620 STRING: 9606.ENSP00000326391 UniGene: Hs.511979 |
BHLHA15 Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA755911LC01HU | BHLHA15 Antibody, FITC conjugated | Human | ELISA |
| CSB-PA755911LA01HU | BHLHA15 Antibody | Human | ELISA, IHC |
| CSB-PA755911LB01HU | BHLHA15 Antibody, HRP conjugated | Human | ELISA |
BHLHA15 Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP755911HU CSB-EP755911HU CSB-BP755911HU CSB-MP755911HU |
Recombinant Human Class A basic helix-loop-helix protein 15(BHLHA15) | Yeast E.coli Baculovirus Mammalian cell |
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