CCDC28B Antibody, Biotin conjugated

Datasheet
Code CSB-PA866287LD01HU
Size US$299
Uniprot No. Q9BUN5
Protocols ELISA Protocol
Immunogen Recombinant Human Coiled-coil domain-containing protein 28B protein (1-76AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance Involved in ciliogenesis. Regulates cilia length through its interaction with MAPKAP1/SIN1 but independently of mTORC2 complex. Modulates mTORC2 complex assembly and function, possibly enhances AKT1 phosphorylation. Does not seem to modulate assembly and function of mTORC1 complex.
Form Liquid
Conjugate Biotin
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Coiled-coil domain-containing protein 28B, CCDC28B
Immunogen Species Homo sapiens (Human)
Research Area Cell Biology
Target Names CCDC28B
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Involved in ciliogenesis. Regulates cilia length through its interaction with MAPKAP1/SIN1 but independently of mTORC2 complex. Modulates mTORC2 complex assembly and function, possibly enhances AKT1 phosphorylation. Does not seem to modulate assembly and function of mTORC1 complex.
Involvement in disease Bardet-Biedl syndrome (BBS)
Subcellular Location Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
Database Links

HGNC: 28163

OMIM: 209900

KEGG: hsa:79140

STRING: 9606.ENSP00000362704

UniGene: Hs.534482

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