CEP164 Antibody, HRP conjugated

Datasheet
Code CSB-PA892491LB01HU
Size US$299
Uniprot No. Q9UPV0
Protocols ELISA Protocol
Immunogen Recombinant Human Centrosomal protein of 164 kDa protein (1-112AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance Plays a role in microtubule organization and/or maintenance for the formation of primary cilia (PC), a microtubule-based structure that protrudes from the surface of epithelial cells. Plays a critical role in G2/M checkpoint and nuclear divisions. A key player in the DNA damage-activated ATR/ATM signaling cascade since it is required for the proper phosphorylation of H2AX, RPA, CHEK2 and CHEK1. Plays a critical role in chromosome segregation, acting as a mediator required for the maintenance of genomic stability through modulation of MDC1, RPA and CHEK1.
Form Liquid
Conjugate HRP
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Centrosomal protein of 164 kDa (Cep164), CEP164, KIAA1052 NPHP15
Immunogen Species Homo sapiens (Human)
Research Area Epigenetics and Nuclear Signaling
Target Names CEP164
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Still Have Questions? Leave a Message or Start an on-line Chat
Function Plays a role in microtubule organization and/or maintenance for the formation of primary cilia (PC), a microtubule-based structure that protrudes from the surface of epithelial cells. Plays a critical role in G2/M checkpoint and nuclear divisions. A key player in the DNA damage-activated ATR/ATM signaling cascade since it is required for the proper phosphorylation of H2AX, RPA, CHEK2 and CHEK1. Plays a critical role in chromosome segregation, acting as a mediator required for the maintenance of genomic stability through modulation of MDC1, RPA and CHEK1.
Involvement in disease Nephronophthisis 15 (NPHP15)
Subcellular Location Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole, Nucleus
Tissue Specificity Expressed in several cell lines.
Database Links

HGNC: 29182

OMIM: 614845

KEGG: hsa:22897

STRING: 9606.ENSP00000278935

UniGene: Hs.504009

Related Products

CEP164 Antibodies

CEP164 Antibodies for Homo sapiens (Human)

CEP164 Proteins

CEP164 Proteins for Homo sapiens (Human)

Most popular with customers

Newsletters

Get all the latest information on Events, Sales and Offers. Sign up for newsletter today.

Copyright © 2007-2018 www.cusabio.com CUSABIO TECHNOLOGY LLC All Rights Reserved.