CHD1L Antibody, Biotin conjugated

Datasheet
Code CSB-PA803136LD01HU
Size US$299
Uniprot No. Q86WJ1
Protocols ELISA Protocol
Immunogen Recombinant Human Chromodomain-helicase-DNA-binding protein 1-like protein (704-897AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance DNA helicase which plays a role in chromatin-remodeling following DNA damage. Targeted to sites of DNA damage through interaction with poly(ADP-ribose) and functions to regulate chromatin during DNA repair. Able to catalyze nucleosome sliding in an ATP-dependent manner. Helicase activity is strongly stimulated upon poly(ADP-ribose)-binding.
Form Liquid
Conjugate Biotin
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Chromodomain-helicase-DNA-binding protein 1-like (EC 3.6.4.12) (Amplified in liver cancer protein 1), CHD1L, ALC1
Immunogen Species Homo sapiens (Human)
Research Area Epigenetics and Nuclear Signaling
Target Names CHD1L
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function DNA helicase which plays a role in chromatin-remodeling following DNA damage. Targeted to sites of DNA damage through interaction with poly(ADP-ribose) and functions to regulate chromatin during DNA repair. Able to catalyze nucleosome sliding in an ATP-dependent manner. Helicase activity is strongly stimulated upon poly(ADP-ribose)-binding.
Subcellular Location Nucleus
Protein Families SNF2/RAD54 helicase family
Tissue Specificity Frequently overexpressed in hepatomacellular carcinomas.
Database Links

HGNC: 1916

OMIM: 613039

KEGG: hsa:9557

STRING: 9606.ENSP00000358262

UniGene: Hs.191164

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