CTSL Antibody, FITC conjugated

Code CSB-PA006193LC01DSU
Size US$299
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Product Details

Full Product Name Rabbit anti-Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops) CTSL Polyclonal antibody
Uniprot No. Q9GKL8
Target Names CTSL
Alternative Names CTSL antibody; CTSL1Cathepsin L1 antibody; EC 3.4.22.15 antibody; Cathepsin L antibody; Major excreted protein antibody; MEP) [Cleaved into: Cathepsin L1 heavy chain; Cathepsin L1 light chain] antibody
Raised in Rabbit
Species Reactivity Chlorocebus aethiops
Immunogen Recombinant Chlorocebus aethiops Cathepsin L1 protein (114-333AA)
Immunogen Species Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)
Conjugate FITC
Clonality Polyclonal
Isotype IgG
Purification Method >95%, Protein G purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form Liquid
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
(From Uniprot)
Thiol protease important for the overall degradation of proteins in lysosomes. Plays a critical for normal cellular functions such as general protein turnover, antigen processing and bone remodeling. Involved in the solubilization of cross-linked TG/thyroglobulin and in the subsequent release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen. In neuroendocrine chromaffin cells secretory vesicles, catalyzes the prohormone proenkephalin processing to the active enkephalin peptide neurotransmitter. In thymus, regulates CD4(+) T cell positive selection by generating the major histocompatibility complex class II (MHCII) bound peptide ligands presented by cortical thymic epithelial cells. Also mediates invariant chain processing in cortical thymic epithelial cells. Major elastin-degrading enzyme at neutral pH. Accumulates as a mature and active enzyme in the extracellular space of antigen presenting cells (APCs) to regulate degradation of the extracellular matrix in the course of inflammation. Secreted form generates endostatin from COL18A1. Critical for cardiac morphology and function. Plays an important role in hair follicle morphogenesis and cycling, as well as epidermal differentiation. Required for maximal stimulation of steroidogenesis by TIMP1.
Subcellular Location Lysosome. Apical cell membrane; Peripheral membrane protein; Extracellular side. Cytoplasmic vesicle, secretory vesicle, chromaffin granule. Secreted, extracellular space. Secreted.
Protein Families Peptidase C1 family

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