Ccl25 Antibody, Biotin conjugated

Datasheet
Code CSB-PA09189D0Rb
Size US$299
Uniprot No. O35903
Immunogen Recombinant Mouse C-C motif chemokine 25 protein (25-144AA)
Raised in Rabbit
Species Reactivity Mouse
Tested Applications ELISA
Relevance Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9.
Form Liquid
Conjugate Biotin
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias C-C motif chemokine 25 (Chemokine TECK) (Small-inducible cytokine A25) (Thymus-expressed chemokine), Ccl25, Scya25 Teck
Immunogen Species Mus musculus (Mouse)
Protocols ELISA Protocol
Research Area Others
Target Names Ccl25
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
Subcellular Location Secreted
Protein Families Intercrine beta (chemokine CC) family
Tissue Specificity Specifically expressed by thymic dendritic cells. High levels in thymus and small intestine.
Database Links

KEGG: mmu:20300

STRING: 10090.ENSMUSP00000024004

UniGene: Mm.7275

Pathway Chemokine signaling pathway

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