Code | CSB-PA000010 |
Size | US$167 |
Image |
Uniprot No. | P55211 | ||||||||
Target Names | CASP9 | ||||||||
Alternative Names | CASP9; MCH6; Caspase-9; CASP-9; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; APAF-3; ICE-like apoptotic protease 6; ICE-LAP6 | ||||||||
Raised in | Rabbit | ||||||||
Species Reactivity | Mouse,Rat | ||||||||
Immunogen | Synthesized peptide derived from the C-terminal region of Human Caspase-9. | ||||||||
Conjugate | Non-conjugated | ||||||||
Isotype | IgG | ||||||||
Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | ||||||||
Concentration | It differs from different batches. Please contact us to confirm it. | ||||||||
Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. | ||||||||
Form | Liquid | ||||||||
Tested Applications | WB, IHC, ELISA | ||||||||
Recommended Dilution |
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Protocols | Western Blotting(WB) Protocol Immunohistochemistry (IHC) Protocol ELISA Protocol |
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Troubleshooting and FAQs | Antibody FAQs | ||||||||
Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | ||||||||
Lead Time | Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time. | ||||||||
Still Have Questions? | Leave a Message or Start an on-line Chat |
Function | Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).; FUNCTION |
Protein Families | Peptidase C14A family |
Tissue Specificity | Ubiquitous, with highest expression in the heart, moderate expression in liver, skeletal muscle, and pancreas. Low levels in all other tissues. Within the heart, specifically expressed in myocytes. |
Database Links |
HGNC: 1511 OMIM: 602234 KEGG: hsa:842 STRING: 9606.ENSP00000330237 UniGene: Hs.329502 |
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