GPR110 Antibody

Code CSB-PA002753
Size US$100
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  • Western Blot analysis of 3T3 cells using GPR110 Polyclonal Antibody
  • Western Blot analysis of NIH-3T3 K562 cells using GPR110 Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
ADGRF1
Alternative Names
G protein coupled receptor 110 antibody; G protein coupled receptor KPG_012 antibody; G protein coupled receptor PGR19 antibody; G-protein coupled receptor KPG_012 antibody; G-protein coupled receptor PGR19 antibody; GP110_HUMAN antibody; GPR110 antibody; HGPCR36 antibody; KPG_012 antibody; PGR19 antibody; Probable G protein coupled receptor 110 antibody; Probable G-protein coupled receptor 110 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from the C-terminal region of Human GPR110.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, IF, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IF 1:200-1:1000
ELISA 1:40000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Orphan receptor.
Gene References into Functions
  1. Study demonstrated orphan G-protein coupled receptor 110 (GPR110, ADGRF1) as the synaptamide receptor, mediating synaptamide-induced bioactivity in a cAMP-dependent manner. PMID: 27759003
  2. High GPR110 expression is associated with CRLF2-rearranged acute lymphoblastic leukemia. PMID: 28866095
  3. ADGRF1 single-nucleotide polymorphisms role in susceptibility to non-small cell lung cancer PMID: 28968839
  4. The results suggested the possible participation of STAT3 instead of ERK in the GPR110 signaling pathways and progression of glioma. PMID: 28728843
  5. GPR56 and GPR110 are activated by exposure of a cryptic tethered agonist PMID: 25918380
  6. GPR110 is an oncogene overexpressed in lung and prostate cancer PMID: 20149256

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Subcellular Location
Cell membrane; Multi-pass membrane protein.; [Isoform 2]: Secreted.
Protein Families
G-protein coupled receptor 2 family, Adhesion G-protein coupled receptor (ADGR) subfamily
Tissue Specificity
Mainly expressed in the kidney. Up-regulated in lung adenocarcinomas and prostate cancers.
Database Links

HGNC: 18990

OMIM: 617430

KEGG: hsa:266977

STRING: 9606.ENSP00000360299

UniGene: Hs.733762

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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