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Code | CSB-PA866201HB01HU |
Size | US$299 |
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Full Product Name | Rabbit anti-Homo sapiens (Human) IL36RN Polyclonal antibody |
Uniprot No. | Q9UBH0 |
Target Names | IL36RN |
Alternative Names | AI413231 antibody; Family of interleukin 1 delta antibody; FIL1 antibody; FIL1 delta antibody; FIL1(DELTA) antibody; FIL1D antibody; Fil1delta antibody; I36RA_HUMAN antibody; IL 1 delta antibody; IL 1 related protein 3 antibody; IL 1F5 (IL 1HY1, FIL1 delta, IL 1RP3, IL 1L1, IL 1 delta) antibody; Il 1h3 antibody; IL 1HY1 antibody; IL 1L1 antibody; IL 1ra homolog antibody; IL 1ra homolog, IL1F5 (Canonical product IL 1F5a) antibody; IL 1RP3 antibody; IL-1 delta antibody; IL-1-related protein 3 antibody; IL-1F5 antibody; IL-1HY1 antibody; IL-1L1 antibody; IL-1ra homolog 1 antibody; IL-1RP3 antibody; IL1F5 antibody; IL1HY1 antibody; IL1L1 antibody; IL1RP3 antibody; IL36RA antibody; IL36RN antibody; Interleukin 1 delta antibody; Interleukin 1 family member 5 (delta) antibody; Interleukin 1 family member 5 antibody; Interleukin 1 HY1 antibody; Interleukin 1 like protein 1 antibody; Interleukin 1 receptor antagonist homolog 1 antibody; Interleukin 36 receptor antagonist antibody; Interleukin-1 delta antibody; Interleukin-1 family member 5 antibody; Interleukin-1 HY1 antibody; Interleukin-1 receptor antagonist homolog 1 antibody; Interleukin-1-like protein 1 antibody; Interleukin-36 receptor antagonist protein antibody; MGC29840 antibody; PSORP antibody; RP23-176J12.6 antibody |
Raised in | Rabbit |
Species Reactivity | Human |
Immunogen | Recombinant Human Interleukin-36 receptor antagonist protein (1-155AA) |
Immunogen Species | Homo sapiens (Human) |
Conjugate | HRP |
Clonality | Polyclonal |
Isotype | IgG |
Purification Method | >95%, Protein G purified |
Concentration | It differs from different batches. Please contact us to confirm it. |
Buffer | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Form | Liquid |
Tested Applications | ELISA |
Protocols | ELISA Protocol |
Troubleshooting and FAQs | Antibody FAQs |
Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Lead Time | Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time. |
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Function | Inhibits the activity of interleukin-36 (IL36A,IL36B and IL36G) by binding to receptor IL1RL2 and preventing its association with the coreceptor IL1RAP for signaling. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor. Proposed to play a role in skin inflammation. May be involved in the innate immune response to fungal pathogens, such as Aspergillus fumigatus. May activate an anti-inflammatory signaling pathway by recruiting SIGIRR. |
Gene References into Functions |
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Involvement in disease | Psoriasis 14, pustular (PSORS14) |
Subcellular Location | Secreted |
Protein Families | IL-1 family |
Tissue Specificity | Predominantly expressed in skin keratinocytes but not in fibroblasts, endothelial cells or melanocytes. Detected also in the spleen, brain leukocyte and macrophage cell types. Increased in lesional psoriasis skin. |
Database Links |
HGNC: 15561 OMIM: 605507 KEGG: hsa:26525 STRING: 9606.ENSP00000259212 UniGene: Hs.516301 |